Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases
نویسندگان
چکیده
منابع مشابه
Measurement of iron concentration in human brain using Quantitative Susceptibility Mapping (QSM): correlation with age
Introduction: Excessive iron deposition is often associated with neurodegenerative disorders, such as Parkinson’s disease (PD), Alzheimer’s disease and Huntington’s Chorea [1]. Quantitative measurement of regional iron deposition in the brain may help with diagnosis and assessment of disease progression. In order to use iron deposition as a new biomarker to stratify the stages of diseases, it i...
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Quantitative susceptibility mapping (QSM) is a novel technique which allows determining the bulk magnetic susceptibility distribution of tissue in vivo from gradient echo magnetic resonance phase images. It is commonly assumed that paramagnetic iron is the predominant source of susceptibility variations in gray matter as many studies have reported a reasonable correlation of magnetic susceptibi...
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BACKGROUND This study explores the magnetostatic properties of the Alzheimer's disease brain using a recently proposed, magnetic resonance imaging, postprocessed contrast mechanism. Quantitative susceptibility mapping (QSM) has the potential to monitor in vivo iron levels by reconstructing magnetic susceptibility sources from field perturbations. However, with phase data acquired at a single he...
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Introduction Quantitative susceptibility mapping (QSM) is a new contrast mechanism in magnetic resonance imaging (MRI). The images produced by the QSM enable researchers and clinicians to easily localize specific structures of the brain, such as deep brain nuclei. These nuclei are targets in many clinical applications and therefore their easy localization is a must. In this study, we aimed to i...
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Susceptibility-weighted imaging (SWI) is a magnetic resonance imaging (MRI) technique that enhances image contrast by using the susceptibility differences between tissues. It is created by combining both magnitude and phase in the gradient echo data. SWI is sensitive to both paramagnetic and diamagnetic substances which generate different phase shift in MRI data. SWI images can be displayed as ...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2021
ISSN: 1662-453X
DOI: 10.3389/fnins.2021.618435